Epigenetic Regulation of normal hematopoiesis and its dysregulation in myeloid neoplasia

Funktionelle Untersuchungen zur Rolle der H3K4 Methyltransferasen bei myeloider Neoplasie






  • Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, Anastassiadis K, Stunnenberg HG, Stewart AF. Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant. Development. 2014 Feb;141(3):526-37. PMID:24423662


  • Singh, R. P., Franke, K., Kalucka, J., Mamlouk, S., Muschter, A., Gembarska, A., Grinenko, T., Willam, C., Naumann, R., Anastassiadis, K., Stewart, A. F., Bornstein, S., Chavakis, T., Breier, G., Waskow, C. and Wielockx, B. HIF prolyl hydroxylase 2 (PHD2) is a critical regulator of hematopoietic stem cell maintenance during steady-state and stress. Blood. 2013 Jun 27;121(26):5158-66. PMID:23667053

  • Francis Stewart


    Technische Universität Dresden
    Biotechnologisches Zentrum (Biotec)
    Tatzberg 47/49
    01307 Dresden
    Telefon: 0351 46340129
    Telefax: 0351 46340143


    Andrea Kranz


    Technische Universität Dresden
    Biotechnologisches Zentrum (Biotec)
    Tatzberg 47/49
    01307 Dresden
    Telefon: 0351 46340152
    Telefax: 0351 46340143


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