Epigenetic Regulation of normal hematopoiesis and its dysregulation in myeloid neoplasia
Development of integrative methods for the analysis of epigenetic data on myeloid neoplasia
Leiter: Brors, Benedikt
Dissecting the role of PIWIL4 as a novel epigenetic factor in acute myeloid leukemia
Leiter: Buske, Christian; Rawat, Vijay Pal Singh
Disordered epigenetic regulation of the CREBBP oncoprotein and of micro-RNA transcription in juvenile myelomonocytic leukemia at high risk of relapse
Leiter: Flotho, Christian
Functional analysis of somatic cancer mutations in human DNA methyltransferases
Leiter: Jeltsch, Albert
Reversible histone acetylation and its inhibitors in myeloid neoplasia
Leiter: Jung, Manfred
Epigenetic function of RUNX1 with PRMT6 in normal and aberrant myeloid differentiation
Leiter: Lausen, Jörn
Computational model of epigenetic regulation of myeloid differentiation during homoeostasis and malignant transformation
Leiter: Löffler, Markus; Galle,Jörg, Jörn
Combined epigenetic therapy of acute myeloid leukemia: translational studies of in vivo induction of gene expression and DNA hypomethylation
Leiter: Lübbert, Michael
Comparative characterization of azacytidine-induced RNA and DNA demethylation in myeloid leukemia
Leiter: Lyko, Frank
Functional analysis of KDM6A histone demethylase in the regulation of HSC development and in leukemogenesis
Leiter: Müller, Albrecht M.; Becker, Matthias
The significance of DNA methyltransferase inhibition and DNA methylation for therapy response in acute myeloid leukemia
Leiter: Müller-Tidow, Carsten
Epigenetic dysregulation of transcription factor NF-E2 expression in the pathophysiology of myeloproliferative neoplasms
Leiter: Pahl, Heike
Genetic and epigenetic search for tumor suppressor genes on chromosome 7q in acute myeloid leukemia
Leiter: Plass, Christoph; Döhner, Hartmut; Lipka, Daniel
Functional evaluation of DNA methylation-controlled leukemia stem cell genes
Leiter: Rosenbauer, Frank; Andrade-Navarro, Miguel; Savelyeva, Irina
Epigenetic consequences of MLL fusion protein expression
Leiter: Slany, Robert
Functional examination of H3K4 methyltransferases in myeloid neoplasia
Leiter: Stewart, Francis; Kranz, Andrea